Acthar Gel offers flexible dosing for your patients1

Dosage and frequency should be individualized according to the medical condition, severity of the disease, and initial response of the patient1

  • Acthar Gel is administered as a self-injection or given by a caregiver, which gives patients the flexibility to take it at home or wherever is best for them1
  • Acthar Gel is a gel preparation designed to provide a prolonged release of medication after injection1
  Recommended Dosing From the Label Additional Dosing From Clinical Experience With Acthar Gel
Indication Acthar Gel DM/PM2
Source Acthar Gel Prescribing Information Prospective, open-label proof-of-concept study (N=10)
Injection Subcutaneous or intramuscular Subcutaneous
Dose* 40-80 units
(0.5-1 mL)
80 units (1 mL)
Schedule Every 1-3 days Twice weekly for 24 weeks
Indication Acthar Gel SLE3
Source Acthar Gel Prescribing Information Prospective, open-label study (N=10)
Injection Subcutaneous or intramuscular Subcutaneous
Dose* 40-80 units 
(0.5-1 mL)
80 units (1 mL)
Schedule Every 1-3 days Once daily for 10 days (optional 5-day extension)
Indication Acthar Gel RA4
Source Acthar Gel Prescribing Information Two-part, multicenter randomized withdrawal study 
(N=259)
Injection Subcutaneous or intramuscular Subcutaneous
Dose* 40-80 units 
(0.5-1 mL)
80 units (1 mL)
Schedule Every 1-3 days Twice weekly for 12-24
Indication Acthar Gel Symptomatic Sarcoidosis5
Source Acthar Gel Prescribing Information Retrospective chart review (N=47)
Injection Subcutaneous or intramuscular Subcutaneous or intramuscular
Dose* 40-80 units 
(0.5-1 mL)
40-80 units (1 mL)
Schedule Every 1-3 days Twice weekly for ≥6 months
Indication Acthar Gel Psoriatic Arthritis6
Source Acthar Gel Prescribing Information Prospective, open-label study (N=15)
Injection Subcutaneous or intramuscular Subcutaneous
Dose* 40-80 units 
(0.5-1 mL)
80 units (1 mL)
Schedule Every 1-3 days Twice weekly for 12-24 weeks
  Recommended Dosing 
From the Label
  Additional Dosing From Clinical Experience With Acthar Gel
Indication Acthar Gel DM/PM2 SLE3  RA4 Symptomatic Sarcoidosis5  Psoriatic Arthritis6
Source Acthar Gel Prescribing Information Prospective, open-label proof-of-concept study
(N=10)
Prospective, open-label study
(N=10)
Two-part, multicenter randomized withdrawal study 
(N=259)
Retrospective chart review
(N=47)
Prospective, open-label study
(N=15)
Injection Subcutaneous or intramuscular Subcutaneous Subcutaneous Subcutaneous Subcutaneous or intramuscular Subcutaneous
Dose* 40-80 units (0.5-1 mL) 80 units
(1 mL)
80 units
(1 mL)
80 units
(1 mL)
40-80 units
(1 mL)
80 units
(1 mL)
Schedule Every 1-3 days Twice weekly for 24 weeks Once daily for 10 days (optional 5-day extension) Twice weekly for 12-24 weeks Twice weekly for ≥6 months Twice weekly for 12-24 weeks

*Acthar Gel is provided as a 5-mL multidose vial containing 80 USP units per mL.1